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DM1-SMCC - CAS# 1228105-51-8 11440 SU6656 induces caspase-independent cell death

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Description

SU6656 induces caspase-independent cell death in FRO anaplastic thyroid carcinoma cells and therapeutic synergy in human synovial sarcoma growth

WO2015058191A1

Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment

Exhibits antitumor activity and stimulates interferon-β secretion in tumors

administration is less than 10 min

DM1-SMCC - CAS# 1228105-51-8 11440 SU6656 induces caspase-independent cell deathDM1 SMCC (SMCC DM1) is an antibody drug conjugate (ADC) linker consists of a potent microtubule disrupting agent DM1 and a linker SMCC. Product information CAS Number: 1228105 51 8 Molecular Weight: 1072. 61 Formula: C51H66ClN5O16S Chemical Name: 2,5 dioxopyrrolidin 1 yl 4 ({3 [(2 {[(2S) 1 {[(1S,2R,3S,5S,6S,20R,21S) 11 chloro 21 hydroxy 12,20 dimethoxy 2,5,9,16 tetramethyl 8,23 dioxo 4,24 dioxa 9,22 diazatetracyclo[19. 3. 1. 1,. 0,]hexacosa

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